No it's not? If you don't know what you're talking about (and this is directed mostly at TrekPL and SharpSabre) I suggest you don't comment - it's not like you have to.
Latest Mangos for 2.4.3 is the backport from
8757 at the moment. You can find it's changelog
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- as you can see, latest update was today and no, you don't need any downgrade patch (though you do need a downgrade patch to get the latest ScriptDev2 to work with that, but that's another story). Our server is currently running 8719 which works like a charm - you can find our compiled binaries
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(but find your own DB, if you can't you should use a repack).
Ontopic then: the latest AntiCheats I have seen were for older cores unfortunately. There is however an interesting discussion going on at Mangos forums concerning [ame=http://www.getmangos.com/community/showthread.php?t=8866]Warden[/ame] - that would prevent a lot of hacking all in one go. Worth keeping an eye on I suppose.